Final Project HFT4413 Hospitality Analytics and R Original Essay Help

Final Project HFT4413 Hospitality Analytics and R Original Essay Help

Write a simple discussion on the effect of PSP on these novel proteins ( Calumenin, Caveolin-3, PDZ and LIM domain protein 1 and Coiled-coil domain-containing protein 61) expressed in differentiated H9c2 cells and the possible consequence when these proteins are affected. I prefer each protein written in a separate paragraph . and please I do not want references from the internet or sites or from books. I just want it from articles.Below is the aim, method and result of my study , hope this will help.AimIn order to understand the molecular basis for the potential long-term toxicity of PSP. The study will focus on their effects on the expression of novel proteins in differentiating H9c2 rat cardiomyocyte-like cells detected by Mass spectrometry .MethodsH9c2 cells were induced to differentiated for 7 days in the presence of PSPResultsIt was found that sublethal concentration 3 ‘M PSP had a significant decrease on the expression of novel cardiac cytoskeleton proteins, which are ( Calumenin, Caveolin-3, PDZ and LIM domain protein 1 and Coiled-coil domain-containing protein 61)These proteins are probably closely associated with the morphological changes such as observed in experiments. Thus, these findings may represent a molecular mechanism for long-term OP-induced cytotoxicity in differentiating H9c2 cells. This is the first study to report the effect of sublethal concentrations of OPs in cardiac-like cells.


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