STA 137 Project Description of the data: This proj Assignment Assistance

STA 137 Project Description of the data: This proj Assignment Assistance

auto; -webkit-text-stroke-width: 0px;Assignment (20 points) BIOL2020UIn this problem set you will be looking at different mutant populations using aclassical genetics simulator (CGS) program. The idea is that you will be actingas the geneticist and attempting to determine the inheritance patterns of thesedifferent populations. For each population that you will be analyzing you do notknow the mode of inheritance and/or the genotypes of the phenotypic traitsdisplayed by the organisms. Your task is to conduct controlled crosses anddetermine the mode of inheritance.Each time you open a problem in CGS, you are given a new population. You willuse the individuals in these populations to preform your crosses to determinethe mode of inheritance.1. You will need to determine if the probable mode of inheritance is: £ dominant or recessive or co-dominant or lethal or multiple alleles £ sex-linked or autosomal £ due to multiple linked or unlinked genes (if genes are linked you will need todetermine map distances)2. The genotype that is associated with each of the phenotypes and theratios that you expect for the genotypes and phenotypes.You will be submitting an individual assignment but you can consult with yourclass mates.You should work on the practice populations, to familiarize yourself with the CGSprogram. The practice populations will give you some experience with theprogram so that you can develop strategies to do the assignment. These will notbe graded.When you are ready to do the assignment, enter your name and you can startwork on the different populations.Each population has a different inheritance pattern. Note that the populationsyou work with will be unique for you and not the same as your classmates.Write a report summarizing your findings:You will be submitting a report that shows how you determined the mode ofinheritance for each of the populations that you worked with. Make sure that youprovide the evidence that supports your conclusions. This will include the resultsof key crosses and any statistical analysis that you did to test your hypothesis. Follow the assignment template that has been posted for the practice population.As mentioned above, the primary goals of this assignment are to determine:1. the probable mode of inheritance of each phenotypic trait,2. the genotypes associated with each phenotype and3. the ratios of genotypes and phenotypes expected in crosses if your model iscorrect.Some general hints about how to approach the assignment: focus on one trait at a time. determine which phenotype is dominant and which is recessive. find homozygotes.As you work through the populations ask yourself these questions:1. Which crosses did you do? Include details.2. What did you want learn from each of the crosses that you performed? Thatis, what information could the proposed cross provide about the inheritance ofthegene?3. Did the results support your assumptions about the genetics of the trait? Whatdo the results tell you about the genotypes? Did your hypothesis change? If itdid, what new crosses do you need to do to test your new hypothesis?Use all of this information to help you develop a strategy to solve the problemsas well as to assist you in writing your report. Results from crosses can becopied directly from CGS.Submit your final report in Blackboard in the assignment dropbox provided. Getting Started (you can also visit cgslab.com/getstarted/ for instructions)1. ACCESS THE PROGRAM at: www.cgslab.com/student.htmla. Click on the Login to Your Account.b. On the next screen Click on either [New Student Collect New Organisms ]or [Returning Student Retrieve Saved Organisms ] to begin.c. Enter the Course ID [uoit] and the appropriate Student Account [practice orassignment] click the Next button. (For a demo use login = cgs and password =demo.)d. Enter your name.e. Copy the PASSWORD. This will allow you to return to saved problems. Thenclick [OK, I wrote down my password]f. Click on the First problem, e.g. [Drosophila 1] to highlight it and then click on[START CROSSING]. Read the information on the screen that appears and click[Continue]. Be sure to save your crosses each time that you exit or all your workwill be lost and you will get a different population next time you login.g. The white collection tray that appears contains all of the flies (or mice orplants) you have from a Wild population. Pull-down menus at the top of the tray allow you to Sort by or View the flies byvarious phenotypic traits The Analysis tab at the bottom of the tray gives you numerical (summary) datafor the fly vial. The Stats toggle allows you to do Chi-Square analysis.2. IDENTIFYING PHENOTYPES: As you mouse over each fly (or mouse or plant), its phenotype appears in thegrey block at the bottom of the collection tray.3. PERFORMING CROSSES: Choose the individuals/phenotypes you want and then click on an appropriatefemale from the population and it will appear in the crossing window at the rightside of the screen. Do the same for a male individual. Note that with Arabidopsisit is possible to self individuals. Click [Cross flies] (or mice or plants). A new vial (or line or pan) with the offspring from the above cross will appear.4. RECORDING YOUR CROSSES AND THEIR RESULTS: Click the [Analysis] button at the bottom of the offspring collection tray. Note: You may wish to write notes about the crosses in the Notes space at thebottom of the Analysis screen. You can later download the summary data andyour notes from all vials by clicking [View All Data] (in the lower right handcorner of the screen) and copying and pasting the data tables and notes into aWord file. (Use courier font to maintain columns and rows.) Record all of this information in your notes and/or Word document.


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